Applications of indee labs platform

Our microfluidic gene delivery platform can be used for gentle, scalable, and viral-free delivery of a range of molecules to several cell types, including human primary immune cells. Our team works with you to validate our platform for your specific applications.

μVS is a platform technology

Development pipeline

Info Device Proof of Concept Optimization
PMBCs or T cells
mRNA Toggle more info 85%
We demonstrate efficient mRNA expression of enhanced green fluorescent protein (EGFP) (e.g., 57.4 ± 6.8% of viable, recovery cells, mean ± stdev) after mRNA delivery to primary human T cells with high cell viability (e.g., 83.7 ± 0.7% of recovered cells), high cell recovery (e.g., 96.3 ± 1.1% of processed cells), and minimal alteration to T cell activation profile.
Cas9 RNPs (CRISPR) Toggle more info 60%
We are currently delivering Cas9 RNP complex to knock out and modify functional T cell markers. Please contact us for more information.
Plasmids Toggle more info 55%
We currently performing a delivery screen of plasmids ranging from 2-10kb into human primary T cells. In addition, we are developing a non-viral method for stable and persistent gene modification. Get in touch for more information.